Products  /  Endpoints
Ozette Endpoints · Includes Resolve

Biomarker endpoints at the speed of your trial.

Automated, reproducible flow and spectral cytometry endpoint analysis for clinical development — with no cap on the number of endpoints, samples, or interim analyses.

app.ozette.com · Endpoints
Pre-defined Endpoints — gating treePre-defined EndpointsUpstreamPBMCsNot [CD123+HLADR-]CD19-CD20-CD3+TCRgd+CD3-TCRgd-CD3+TCRgd-CD14-CD66b-CD66b-HLADR-CD66b-HLADR+CD14-CD66b-CD14-CD14-CD16-CD56+CD56-CD27-CD57-CD27-CD57+CD27+CD57-CD27+CD57+CD16-CD56-CD16-CD56+CD16+CD56-CD11c-CD123+CD1c+CD141-CD4-CD8+CD4+CD8-CCR7-CD45RA+CD127-CD25+CCR7-CD45RA-CD27-CD28+XCD3YTCRgdAxesEXPERIMENT-WIDEPlot SizeMGroup ByVISITGroup RowsCMV_STATUS
V1 — CD3 by TCRgd gated dot plot, 2,257 eventsV2 — CD3 by TCRgd gated dot plot, 1,343 eventsV3 — CD3 by TCRgd gated dot plot, 1,710 events
Pre-defined endpoints · grouped by visit
The problem

Clinical biomarker analysis is the bottleneck. It shouldn't be.

Manual analysis can't keep pace with a trial — and can't be trusted to stay consistent across it.

01

Slow, biased gating

Hand gating is laborious and varies by analyst — the same data can yield different answers.

02

Doesn't scale

Trial sample volumes overwhelm manual workflows, so analysis falls behind the study.

03

Late & inconsistent

Results arrive months after the data and drift across sites — too late and too variable for decisions.

What Endpoints does

One locked pipeline. Every sample, analyzed the same.

Endpoints turns your validated panel into a locked, reproducible analysis pipeline, then runs it automatically on trial data as it arrives — consistent across analysts, sites, and the full timeline of the study.

✓ Resolve is built in   so your spectral data is cleanly unmixed before a single endpoint is calculated.

How it works

Set it up once. It runs for the whole study.

Set up your pipeline

We configure a reproducible pipeline from your panel, pre-defined endpoints, and gating sequence.

Run as data arrives

Samples are processed automatically — including interim analyses mid-study — with no limit on volume.

Review, approve, export

Your team reviews and approves gates in an interactive dashboard, then exports figures and summary data.

Days, not months
No limit on endpoints, samples, or analyses
Reproducible across analysts & sites
Interim analysis throughout the study
Built for regulated work

The rigor your trial demands, applied to the analysis behind it.

Endpoints runs under a robust quality management system that meets or exceeds applicable regulatory guidelines — so the analysis stands up to the same scrutiny as the rest of your study.

QMSValidated quality management system
ReproducibleLocked pipeline, identical every run
AuditableReviewable, approvable, exportable
Interim-readyAnalysis throughout the study
Two ways to run it

Operate it yourself, or hand us the whole workflow.

Self-serve software

Your team drives it

Operate Endpoints directly — buy a license and pay only for the files you process. We onboard and train you to run it yourself.

  • License + pay-per-file
  • Onboarding & training included
  • Full control of your pipeline
Managed service + Ozette Lab

We deliver results

We generate high dimensional spectral data under GCLP and run the analysis end-to-end. You get trial-ready results, not a workflow to manage.

  • High dimensional spectral data generation
  • GCLP-compliant, end-to-end
  • Ozette scientists run the analysis
Where Endpoints sits

Tier two — and it includes Resolve.

Unmixing is handled for you. When teams need to go beyond pre-defined endpoints — to find rare or uncharacterized populations — Discovery adds unbiased annotation on top of everything here.

Discovery

Every cell population, annotated

Tier 3 · adds on top

Endpoints

Automated trial biomarker analysis

You are here

Resolve

Adaptive spectral unmixing

Tier 1 · included
Get started

See Endpoints on your own trial data.

Walk through your panel and endpoints with our team.