Publications

Read all about what we’ve been up to in our latest news and recent publications.

Applying Ozette Discovery™ to CITE-seq data to identify predictors of disease.

Methods such as CITE-seq simultaneously measure RNA and protein expression at a single cell level, but the protein expression data is frequently underutilized. Download our preprint to learn how we harness Ozette Discovery™ to achieve instantaneous in silico sorting of granular cell phenotypes, enabling identification of COVID-19-associated cell populations and precise RNA-seq profiling in mixed samples.

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Effective comparison of single-cell embedding visualizations. 

At ISMB 2023, Ozette’s Trevor Manz lead a lively panel on effective comparison of single-cell embedding visualizations. To better understand the approach, challenges, and conclusions, learn more by downloading the event poster here.

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Automated gating and antigen-specific T cells subset discovery using FAUST and COMPASS on ICS data. 

At ISMB 2022, Ozette Computational Biologist Malisa Smith, and Ozette Co-Founder Evan Greene, PhD VP of Quantitative Methods discussed automated gating and antigen-specific T cells subset discovery using FAUST and COMPASS on ICS data as well as how they reanalyzed a published Intracellular Cytokine Staining (ICS) dataset. Download the poster to learn more about their presentation.

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Discovering data transformations for effective visualization of single-cell embeddings. 

At ISMB 2022, Ozette’s Fritz Lekschas, PhD, Head of Visualization Research lead a fascinating discussion about data transformations for effective visualization of single-cell embeddings. If you weren’t able to attend, take a look at this beautiful and though provoking work.

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From assay to endpoints, see how Ozette’s proprietary processes deliver results.

Recently, at CYTO 2023, we showcased how Ozette Endpoints™ and Ozette Discovery™ technologies leverage Artificial Intelligence and Machine Learning to deliver robust computational analysis pipelines and allow for rapid insights into complex high-dimensional data. View process details, methods, and case study examples in our detailed conference poster.

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Vaccination induces HIV broadly neutralizing antibody precursors in humans.

Broadly neutralizing antibodies (bnAbs) can protect against HIV infection but have not been induced by human vaccination. A key barrier to bnAb induction is vaccine priming of rare bnAb-precursor B cells. In a randomized, double-blind, placebo-controlled phase 1 clinical trial...

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